Tyrion Was A Trash Hand to the Dragon Queen, Period

In Game of Thrones, it doesn't seem like Tyrion's (Peter Dinklage) intention to fail dastardly as Daenerys' hand. But fail he did.

Tyrion "Sure Monologues A Lot" Lannister has been a thorn to some sides since murdering Shae at the end of season four, a sweet, spirited character everyone nastily reduces to as "whore." Tyrion would continue referring her as the woman he loved without remembering telling her to leave (an overused "cruel to be kind" noble act typically reserved for male heroes) and then strangling her before letting her have a word in. A man this toxic shouldn't be a hand including to a woman like Daenerys Stormborn, Mother of Dragons, Breaker of Chains, Targaryen. He sabotaged her from the day of his kidnapped arrival in Meereen.

Tyrion has to get rid of Jorah (Iain Gain) out of the way. Luckily for Tyrion, Daenarys still hasn't forgiven Jorah for betraying her.

It is easy for smooth talking Tyrion to swoop in and advise Daenerys to banish the treasonous Jorah again. However, Jorah saves her life and she flees with Drogon, leaving Meereen to the responsibility of Tyrion, Grey Worm, and Missandei. The plan is conceived by Daario Naharis and Tyrion feels more than capable with his buddy Varys. In his undeserved role as temporary ruler, he unchains the other two dragons, coaxes Grey Worm and Missandei to lie and drink wine, and issues a pact with the Good Masters. The latter falls through completely, upstarting a war on the vulnerable city. Daenerys returns just in time and finally obtains enough ships to return home. However, she has little to say on Tyrion's failure as temporary ruler. This alarming red flag swept beneath the rug of male writers/directors. They have forgotten that Daenerys can be quite outspoken and angry if things don't go accordingly for her.

An uncomfortable Tyrion doesn't like the way Daenerys uses her dragon children to intimidate people.

Tyrion really starts screwing up again once Daenerys, her dragons, advisors, and army reach Dragonstone, having advised her to allow Daario to keep the peace in Meereen (wonder how that's going). His plan to take Casterly Rock falls through because Cersei is one step ahead, bombing the Unsullied ships and clearing out the food. They also lose the added forces of Terrell's, Greyjoys, and Dorne, all wiped out and destroyed on the sea. This domino effect begins to take its toll on Daenerys who already has to deal with a visiting Jon Snow. Tyrion is supposedly happy to see Jorah again (a big side eye) and wished him a good journey with Jon and the Wildlings to the North. When they're in trouble, however, Tyrion advises Daenerys not to help them. Did he not inform her that she needed allies? How will she win any support if she left them to die? Plus, Jorah is there. Team Daenerys loves Jorah (save for the whole icky Jorah in love with Dany thing). Unfortunately, Daenerys loses a dragon on this rescue mission. So maybe Tyrion was right on another level.

Also apparently Tyrion is in love with Daenarys. Big gross.

The biggest ruin of his political approaches is Tyrion constantly believing in Cersei, a woman who has tried to have him killed since his birth. He actually, really, truly, genuinely believes that his nasty sister will help him. He asks her for mercy three times. And each time, she does not grant him a damn olive branch. Shame. Shame. Shame. First at the Dragonpit meeting, he leads the discussion and she refuses to provide forces to aide Daenerys and Jon Snow fight the blue-eyed undead alongside the North. Secondly, he talks to her privately in hopes of changing her mind. She does, but it's all a fluke, a funny little hoax to make him feel accomplished. Only Jaime comes to help. Thirdly, before Missandei is horribly executed, he pleads with Cersei otherwise with the worst opening ever, "your people hate you." Talk about the wrong way to negotiate.

Season eight may have been awful (sexist, racially insensitive, various character assassinations, etc), but Peter Dinklage and Emilia Clarke both scored Emmy nominations out of this mess. 

Later, Tyrion outs Varys as a traitor and his friend is burned alive. He then betrays Daenerys again, freeing his brother and having Ser Davos (a man whose son he killed seasons ago) arrange an escape for Jaime and heartless Cersei. That plan fails (ha ha, not sorry). Daenerys kills most of King's Landing including Cersei and Jaime. This pisses Tyrion off. Of course, he must commit one final act of sabotage-- the kiss of death. The show ends with Tyrion being another man's hand (he stays winning). After all, white men always get rewarded in life despite all their big, costly failures and treasons. Plus, murderer Jon Snow/Aeron Targaryen lives out his life sentence at the Night's Watch with his direwolf, Ghost. Certain characters, primarily male, get redemption arcs (Theon Greyjoy, Jaime, and even Tyrion) except Daenerys. She is ultimately destroyed by two men: a former sworn enemy and a nephew by blood (also count in the writers too). It sucks that Tyrion is likely (fictionally speaking) out there being hand by morning and desperately trying to carry out the Lannister line in a brothel by night. His intentions will be to name his kids after Jaime and Cersei (because she is not that evil).

All in all, Daenerys would have been much better off with a hand whose last name was not Lannister.